Menschen, die über Veränderungen in ihren starren, negativen Denkmustern nach dem Konsum von Psychedelika berichteten, erlebten die größte Verbesserung ihrer psychischen Gesundheit. Emotionale Durchbrüche, die durch intensive emotionale Entspannung und neue persönliche Erkenntnisse gekennzeichnet sind, erwiesen sich als stärkster Prädiktor für das Wohlbefinden.

I’ve linked to the news release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:

https://www.tandfonline.com/doi/full/10.1080/02791072.2024.2421892

Abstract

Dysfunctional attitudes – a cornerstone to cognitive psychotherapy – vary with both psychological and pharmacological interventions. Post-acute changes in these cognitions appear to covary with the acute reactions to psychedelics that often precede improved outcomes. An examination of post-acute changes in dysfunctional attitudes could support targeting them in psychedelic-assisted therapy. Screened participants (N = 400+) reported the acute, subjective experiences associated with their most significant psychedelic response as well as post-acute changes in dysfunctional attitudes and subsequent alterations in wellbeing. Dysfunctional attitudes, emotional breakthroughs, and challenging experiences accounted for significant, unique variance in wellbeing. The effects of dysfunctional attitudes generally exceeded those of acute reactions. Comparisons among those acute responses revealed that the effect of emotional breakthroughs exceeded challenging experiences, which exceeded mystical experiences. Nevertheless, the indirect effects through post-acute changes in dysfunctional attitudes did not account for all the impact of acute effects nor interact with them. These results emphasize the import of both acute and post-acute reactions, suggesting that strategies for optimizing each might maximize outcomes for psychedelic-assisted interventions. Furthermore, standard cognitive interventions that alter these cognitions could combine with psychedelics in straightforward ways. The results also support the use of multiple multivariate approaches to address the relative importance of multicollinear predictors.

From the linked article:

Changes in dysfunctional attitudes linked to improved wellbeing after psychedelic use

Recent research published in the Journal of Psychoactive Drugs sheds light on the ways psychedelic experiences might influence mental wellbeing. The study suggests that while intense, subjective reactions during psychedelic use—such as emotional breakthroughs or mystical feelings—contribute to improvements in wellbeing, changes in dysfunctional attitudes after the experience play an even larger role.

The most significant predictor of improved wellbeing was post-acute changes in dysfunctional attitudes. Participants who reported shifts in their rigid, negative thought patterns experienced the greatest enhancements in their mental health, suggesting that these cognitive changes are critical for long-term benefits.

Among the acute subjective experiences, emotional breakthroughs emerged as the strongest predictor of wellbeing. These moments, characterized by intense emotional release and new personal insights, were associated with significant improvements.

Mystical experiences, which involve feelings of unity and transcendence, also correlated with better wellbeing, though their impact was smaller compared to emotional breakthroughs. Challenging experiences, such as feelings of fear or paranoia, were linked to smaller improvements and sometimes negative outcomes, though they appeared to still play a role in the overall therapeutic process.