Ein experimenteller Bluttest erkennt Bauchspeicheldrüsenkrebs im Frühstadium wirksamer als andere verfügbare Tests und identifiziert 71 % der Bauchspeicheldrüsenkrebsproben
Experimental blood test improves early detection of pancreatic cancer
Ein experimenteller Bluttest erkennt Bauchspeicheldrüsenkrebs im Frühstadium wirksamer als andere verfügbare Tests und identifiziert 71 % der Bauchspeicheldrüsenkrebsproben
Experimental blood test improves early detection of pancreatic cancer
1 Comment
>The new test works by detecting two sugars — CA199.STRA and CA19-9 — that are produced by pancreatic cancer cells and escape into the bloodstream. CA19-9 is the current gold-standard biomarker for pancreatic cancer. Haab’s lab identified CA199.STRA as a cancer biomarker and developed the technology to detect it.
>
>On its own, the CA19-9 test correctly identified only 44% of pancreatic cancer samples in the lab. When CA199.STRA was added, the new combination test correctly identified 71% of pancreatic cancer samples.
>
>The combination test also greatly reduced the number of false negatives while maintaining a low false positive rate. Low rates of false positives and false negatives are important because they reflect the test’s ability to correctly identify the presence or absence of cancer.
>
Paper: [A rigorous multi-laboratory study of known PDAC biomarkers identifies increased sensitivity and specificity over CA19-9 alone – ScienceDirect](https://www.sciencedirect.com/science/article/pii/S0304383524006402?via%3Dihub)